Electron Multileaf Collimator (EMLC)

No block absorber

In photon radiotherapy individually shaped irradiation fields are accurately and economically created using the parallel arranged metal leaves of a multileaf collimator (MLC). In contrast, electron beam therapy still requires manufacturing complex patientspecific absorbers. In spite of the therapeutic benefits, electron radiotherapy has been gradually replaced by advanced photon irradiation due to high labour and material costs. Euromechanics has developed a computer-controlled Electron Multileaf Collimator (EMLC) in cooperation with the University Medical Center Hamburg-Eppendorf, Germany (UKE). Since the beginning of 2012, the EMLC is in clinical use at the UKE.

The EMLC was designed as a substitute for all electron applicators and field shaping block absorbers. Additionally, the EMLC enables remote-controlled beam collimation and isocentric dose delivery through multi-directional sequenced fields without patient realignment.

The EMLC – a prizewinning development

A further milestone: In addition to the economical advantages, the EMLC opens up a new vista for the application of IMRT with electrons. “Better adjustment of the dose distribution on near-surface target volumes can be achieved by means of controlled segmentation using different electron energies”, the German Society of Medical Physics (DGMP) states in the awarding of the Elekta Research Prize for the development of the EMLC. Also the German Society of Radiation Oncology (DEGRO) and the European Society for Therapeutic Radiology and Oncology (ESTRO) awarded this development for its purpose to enable IMRT applications in electron radiotherapy.

Optimal therapy of superficial cancers

Intensity-modulated radiation therapy (IMRT) with photons achieves higher conformity between treated volume and tumour volume and better sparing of the surrounding healthy tissue. In the treatment of superficial tumours such as mamma carcinoma or skin melanoma, however, photon IMRT often results in large volume of normal tissue exposed to a low dose. In contrast, electron radiation penetrates the tissue as deep as defined by the electron energy. Therefore, IMRT with electrons limits the irradiated volume and, as a consequence, protects adjacent and underlying healthy tissue and radiosensitive organs of heart and lung.

IMRT with electrons feasible

The EMLC combines the advantages of electron dose delivery and the technological potential of IMRT. The EMLC allows near-surface tumours to be irradiated and treated in a clinically optimal, effective and economical way. Performing IMRT with electrons using the EMLC is subject of further research and development in collaboration with the University Medical Center Hamburg-Eppendorf.

Close to patient

The EMLC can be used with all widely-used linear accelerators. In comparison to add-on photon MLCs, the EMLC is characterized by a compact design and lower total weight and is – all in all – easier to handle. As a result, the EMLC can be positioned as close to the patient as clinically necessary, without colliding with the patient. The EMLC is light-inweight and enables dose delivery from all orientations without relevant tolerances due to gravitation.

The Electron Multileaf Collimator is a product of Euromechanics Solution GmbH

further informations:

pdficonEMLC-Prospekt (englisch, pdf, 1.9 MB)publications

Radiother. Oncol. 94 (2010) 313-318: „Comparison of electron IMRT to helical photon IMRT and conventional photon irradiation for treatment of breast and chest wall tumours” (englisch)

IFMBE Proceedings 25/I (2009) 362-365: „A New Electron IMRT Technique for Breast Cancer: Comparison to Photon IMRT and Conventional Irradiation Based on Static and Dynamic Dose Measurements” (englisch)

Phys. Med. Biol. 54 (2009) 5253-5270: „A dose optimization method for electron radiotherapy using randomized aperture beams” (englisch)

Phys. Med. Biol. 53 (2008) 1071-1085: „Characterization of an add-on multileaf collimator for electron beam therapy” (englisch)

Phys. Med. Biol. 51 (2006) 5987-6003: „Design of a computer-controlled multileaf collimator for advanced electron radiotherapy” (englisch)

Poster Präsentation ESTRO 2012: „Validation of a leaf-sequencing model for electron IMRT providing efficient and robust dose delivery in breast cancer” (englisch, pdf, 0.3 MB)

 

Poster Präsentation AAMP 2007: „Development of an electron multileaf collimator performing computer-controlled beam collimation and isocentric dose delivery with electrons” (englisch, pdf, 0.5 MB)

Universitätsklinikum Hamburg-Eppendorf – Klinik für Strahlentherapie und Radioonkologie

 

Dissertation, Abteilung Physik, Universität Hamburg, 2009: „Implementierung der Intensitätsmodulierten Strahlentherapie mit Elektronen”

Zusammenfassung Dissertation, Abteilung Physik, Universität Hamburg, 2009: „Implementation of intensity-modulated radiation therapy with electrons” (englisch, pdf, 0.7 MB)